Rhamnolipids Nano-Micelles as a Potential Hand Sanitizer

COVID-19 is a pandemic disease caused by the SARS-CoV-2, which continues to cause global health and economic problems since emerging in China late 2019. Until now, there are no standard antiviral treatments. Thus, several strategies were adopted minimize virus transmission, such as social distancing, face covering protection hand hygiene. Rhamnolipids glycolipids produced formally Pseudomonas aeruginosa biosurfactants, they shown have broad antimicrobial activity. In this study, we investigated activity of rhamnolipids against selected multidrug resistant bacteria SARS-CoV-2. growing strain LeS3 new medium formulated from chicken carcass soup. The isolated characterized for their molecular composition, into nano-micelles, antibacterial nano-micelles was demonstrated vitro both Gram-negative Gram-positive drug bacteria. silico studies docking structural non-structural proteins SARS-CoV-2 also performed. We efficient specific interaction with active sites these proteins. Additionally, computational suggested that membrane permeability obtained results indicate could be another target find utility fight COVID-19, future perspective considered.